Effect of electroporation on radiotherapy treatment in human hepatocellular carcinoma cells
نویسندگان
چکیده
Thanks to technological developments and clinical studies in recent years, radiotherapy has been widely used cancer treatment, radiation can be applied effectively cells without harming healthy tissues. However, some types of are resistant which at certain doses that do not harm normal In this context, the main purpose study is increase sensitivity cancerous by doing so reduce negative side effects with lower get more efficient results through combined use treatments. study, HepG2 (Human hepatocellular carcinoma) liver were treated ionizing (210 kV x-ray a dose rate 2.1 Gy/min) or electroporation (1125 V/cm, 100 µs, 1 Hz, 8 square waves) combination these two therapies. Responses treatments determined MTT viability test. It was observed survival significantly decreased group after electroporation. The electrical pulses caused 1.25-fold HepG-2 210 x-ray. These show application before cells.
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ژورنال
عنوان ژورنال: Journal of physical chemistry and functional materials
سال: 2021
ISSN: ['2651-3080']
DOI: https://doi.org/10.54565/jphcfum.1006281